In Vivo Microscopy in the Male and Female Genital Tract

In Vivo Microscopy in the Male and Female Genital Tract
Author(s):    Sabine Kölle; Matthias Trottmann
Published:   2016
DOI:             10.1117/3.2248539
eISBN: 9781510604391
Description:

An in-depth understanding of the morphology and function of organs in the body is pivotal for any health professional. If health is compromised, successful intervention is only possible when the malfunctions can be identified, visualized, and monitored. The imaging technologies described in this Spotlight might contribute to add new diagnostic and therapeutic strategies in the daily routine of clinicians in the future. In the present, these technologies provide valuable tools for researchers to develop new and stunning insights into the physiology and pathology of reproductive biology—a pivotal prerequisite for achieving progress in the diagnosis and therapy of disorders in the reproductive tract. This book is intended to provide new insights in live cell imaging for researchers and physicians working in andrology or gynecology and to stimulate the further development of imaging technologies in the field. As a precise, step-by-step instruction is provided, the book should enable interested researchers to apply these technologies for elucidating their special field of interest and to find answers to pertinent questions.

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Using mouse and bovine models, this Spotlight focuses on the (a) methodology and (b) diagnostic value of two new imaging technologies in order to visualize the physiology and pathology of the male and female genital tracts under in vivo conditions. These methods have been established for their effective use in reproductive medicine by our research team. The following techniques will be covered: (a) digital videomicroscopy and (b) probe-based confocal laser endomicroscopy (pCLE). The aim of the book is to enable researchers to apply these techniques of in vivo microscopy in order to develop new insights into the effects of diseases or drugs on the functional integrity of the male and female genital tracts. Additionally, this book aims to clear the way for the establishment of routine use of pCLE in the daily practice in gynecology and andrology.

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