Time-Resolved and Spatially Modulated Spectroscopy and Tomography of Tissues

doi:10.1117/3.1003040.ch11

Book: Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnostics, Third Edition

Author(s): Valery V. Tuchin

Published: 2015

https://doi.org/10.1117/3.1003040.ch11

Author Affiliations +

Abstract

Time-resolved and spatially modulated optical diffusion techniques and instruments are discussed. A promising technique and device for accurate in vivo measurement are analyzed. In accordance with the basic principles discussed in Chapter 1, four types of time and spatially resolved techniques and instruments are considered: the time domain, which uses ultrashort laser pulses; the frequency domain, which exploits an intensity modulated light and narrow band heterodyne detection; the phased array technique, which utilizes an interference of photon diffusion density waves; and a technique for tissue probing by a spatially modulated light beam.