Quantitative OCT analysis of sperm hyperactivation state in mouse fallopian tube

Zheng-Chen Yao; Shang Wang; Irina Larina

doi:10.1117/12.2610364

2 March 2022 Quantitative OCT analysis of sperm hyperactivation state in mouse fallopian tube

Zheng-Chen Yao, Shang Wang, Irina Larina

Proceedings Volume PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX; PC119590I (2022) https://doi.org/10.1117/12.2610364
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Spermatozoa motility is critical for successfully reaching the egg and fertilization. One of essential transitions in sperm behavior within the female reproductive tract required for fertilization is hyperactivation. Our group established an innovative volumetric in vivo sperm tracking approach using OCT through an intravital imaging window. This study is focused on the development of new functional OCT quantitative measures for the analysis of sperm hyperactivation state. The quantitative parameters were first developed in vitro; then optimized and tested in vivo. This work established a potential quantitative approach for differentiating sperm hyperactivation status based on their trajectories in vivo.

Conference Presentation

Citation Download Citation

Zheng-Chen Yao, Shang Wang, and Irina Larina "Quantitative OCT analysis of sperm hyperactivation state in mouse fallopian tube", Proc. SPIE PC11959, Dynamics and Fluctuations in Biomedical Photonics XIX, PC119590I (2 March 2022); https://doi.org/10.1117/12.2610364

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available