Enhancing the performance of Localization Optoacoustic Tomography (LOT) by aligning motion-affected frames

Jim Zhao; Daniil Nozdriukhin; Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1117/12.2649876

9 March 2023 Enhancing the performance of Localization Optoacoustic Tomography (LOT) by aligning motion-affected frames

Jim Zhao, Daniil Nozdriukhin, Xosé Luís Deán-Ben, Daniel Razansky

Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC1237911 (2023) https://doi.org/10.1117/12.2649876
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Localization optoacoustic tomography (LOT) can significantly enhance the optoacoustic imaging capabilities by providing a spatial resolution beyond the acoustic diffraction barrier and further enabling mapping the blood flow velocity. Higher resolution results in an enhanced sensitivity to cardiac and breathing motion, which can degrade the LOT imaging performance even if the animal is constrained. We suggest a new approach based on aligning the motion-affected frames of the acquired sequence with a reference frame. Localization and tracking of particles is then performed in the corrected sequence. This results in an enhanced imaging performance and more accurate velocity readings.

Conference Presentation

Citation Download Citation

Jim Zhao, Daniil Nozdriukhin, Xosé Luís Deán-Ben, and Daniel Razansky "Enhancing the performance of Localization Optoacoustic Tomography (LOT) by aligning motion-affected frames", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC1237911 (9 March 2023); https://doi.org/10.1117/12.2649876

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