Studies On Endoscopic Local Hyperthermia Using Nd-YAG Laser

H. Tsunekawa; N. Kanemaki; A. Furusawa; M. Hotta; A. Kuroiwa; M. Nishida; N. Mori; Y. Watanabe; K. Morise; A. Iizuka

doi:10.1117/12.937316

10 March 1987 Studies On Endoscopic Local Hyperthermia Using Nd-YAG Laser

H. Tsunekawa, N. Kanemaki, A. Furusawa, M. Hotta, A. Kuroiwa, M. Nishida, N. Mori, Y. Watanabe, K. Morise, A. Iizuka

Proceedings Volume 0712, Lasers in Medicine; (1987) https://doi.org/10.1117/12.937316
Event: Cambridge Symposium-Fiber/LASE '86, 1986, Cambridge, MA, United States

Abstract

Attempting a new method of laser irradiation for depressed gastric carcinoma, using a newly developed interstitial probe and laser attenuator, we applied local hyperthermia with prolonged low watt contact irradiation. Experimental studies were performed with this probe, using BDF1 mice injected hypodermically with Lewis lung carcinoma. A laser power of 2.0 w at the tip of fiber produced the most desirable temperature curve, about 43 - 60°C at the irradiation site. Clinical applications were carried out on 15 patients with early gastric carcinoma (mainly depressed), 10 preoperative pilot cases and 5 inoperable cases. In follow-up operations and biopsies gastric carcinoma was found to have completely dis-appeared in 2 of the preoperative and 4 of the inoperable cases. In the remaining 8 preoperative cases residual traces of carcinoma were found at the margin of the laser ulcer, but not at the bottom of it. We propose that endoscopic local hyperthermia using interstitial probe and low power irradiation (2.0 W) is the safest and most suitable method of dealing with depressed carcinoma.

Citation Download Citation

H. Tsunekawa, N. Kanemaki, A. Furusawa, M. Hotta, A. Kuroiwa, M. Nishida, N. Mori, Y. Watanabe, K. Morise, and A. Iizuka "Studies On Endoscopic Local Hyperthermia Using Nd-YAG Laser", Proc. SPIE 0712, Lasers in Medicine, (10 March 1987); https://doi.org/10.1117/12.937316

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