Grid-based visual aid for enhanced microscopy screening in diagnostic cytopathology

Christos Riziotis; Evangelos Tsiambas

doi:10.1117/12.2246515

31 October 2016 Grid-based visual aid for enhanced microscopy screening in diagnostic cytopathology

Christos Riziotis, Evangelos Tsiambas

Author Affiliations +

Proceedings Volume 10024, Optics in Health Care and Biomedical Optics VII; 100244M (2016) https://doi.org/10.1117/12.2246515
Event: SPIE/COS Photonics Asia, 2016, Beijing, China

Abstract

A grid acting as a spatial reference and calibration aid, fabricated on glass cover slips by laser micromachining and attached on the carrier microscope slide, is proposed as a visual aid for the improvement of microscopy diagnostic procedure in the screening of cytological slides. A set of borderline and also abnormal PAP test cases -according to Bethesda 2014 revised terminology- was analyzed by conventional and grid based screening procedures, and statistical analysis showed that the introduced grid-based microscopy led to an improved diagnosis by identifying an increased number of abnormal cells in a shorter period of time, especially concerning the number of pre- or neoplastic/cancerous cells.

Citation Download Citation

Christos Riziotis and Evangelos Tsiambas "Grid-based visual aid for enhanced microscopy screening in diagnostic cytopathology", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100244M (31 October 2016); https://doi.org/10.1117/12.2246515

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