Flexible microwave ablation applicator for the treatment of pulmonary malignancies

Austin Pfannenstiel; Tom Keast; Steve Kramer; Henky Wibowo; Punit Prakash

doi:10.1117/12.2255504

22 February 2017 Flexible microwave ablation applicator for the treatment of pulmonary malignancies

Austin Pfannenstiel, Tom Keast, Steve Kramer, Henky Wibowo, Punit Prakash

Proceedings Volume 10066, Energy-based Treatment of Tissue and Assessment IX; 100660M (2017) https://doi.org/10.1117/12.2255504
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Microwave ablation (MWA) is an emerging minimally invasive treatment option for malignant lung tumors. Compared to other energy modalities, such as radiofrequency ablation, MWA offers the advantages of deeper penetration within high impedance tissues such as aerated lung, shorter treatment times, and less susceptibility to the cooling heat-sink effects of air and blood flow. Previous studies have demonstrated clinical use of MWA for treating lung tumors; however, these procedures have relied upon the percutaneous application of rigid microwave antennas. The objective of our work was to develop and characterize a novel flexible microwave applicator which could be integrated with a bronchoscopic imaging and software guidance platform to expand the use of MWA as a treatment option for small (< 2cm) pulmonary tumors. This applicator would allow physicians an even less invasive, immediate treatment option for lung tumors identified within the scope of current medical procedures. It may also improve applicator placement accuracy and increase efficacy while minimizing the risk of procedural complications. A 2D-axisymmetric coupled FEM electromagnetic-heat transfer model was implemented to characterize expected antenna radiation patterns, ablation size and shape, and optimize antenna design for lung tissue. A prototype device was fabricated and evaluated in ex vivo tissues to verify simulation results and serve as proof-of-concept. Additional experiments were conducted in an in vivo animal model to further characterize the proposed system.

Citation Download Citation

Austin Pfannenstiel, Tom Keast, Steve Kramer, Henky Wibowo, and Punit Prakash "Flexible microwave ablation applicator for the treatment of pulmonary malignancies", Proc. SPIE 10066, Energy-based Treatment of Tissue and Assessment IX, 100660M (22 February 2017); https://doi.org/10.1117/12.2255504

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available