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The papers in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. Additional papers and presentation recordings may be available online in the SPIE Digital Library at SPIEDigitalLibrary.org. The papers reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon. Please use the following format to cite material from these proceedings: Author(s), “Title of Paper,” in Medical Imaging 2017: Digital Pathology, edited by Metin N. Gurcan, John E. Tomaszewski, Proceedings of SPIE Vol. 10140 (SPIE, Bellingham, WA, 2017) Seven-digit Article CID Number. ISSN: 1605-7422 ISSN: 2410-9045 (electronic) ISBN: 9781510607255 ISBN: 9781510607262 (electronic) Published by SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA Telephone +1 360 676 3290 (Pacific Time) · Fax +1 360 647 1445 Copyright © 2017, Society of Photo-Optical Instrumentation Engineers. Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at copyright.com. Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1605-7422/17/$18.00. Printed in the United States of America. Publication of record for individual papers is online in the SPIE Digital Library.
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AuthorsNumbers in the index correspond to the last two digits of the seven-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first five digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B…0Z, followed by 10-1Z, 20-2Z, etc. Abe, Tokiya, 0U Ablove, Tova, 05 Aichinger, Wolfgang, 0N Andersson, Emilia, 07 Andersson, Mats, 0O Antulov-Fantulin, Nino, 03 Arora, Ashish, 0H Arvidsson, Ida, 0S Aström, Kalle, 0S Atzori, Manfredo, 0O Avanaki, Ali R. N., 0Y Badano, Aldo, 0R Baust, Maximilian, 0F Beamer, Gillian, 0J Ben Cheikh, Bassem, 0C Benz, Michaela, 0B, 0N Bird, Benjamin, 04 Bjartell, Anders, 0S Bor-Angelier, Catherine, 0C Brbić, Maria, 03 Bredno, Joerg, 07 Brennan, Patrick C., 02 Cetin, A. Enis, 0N Cetin-Atalay, Rengul, 0N Chang, Young Hwan, 0T Chen, W., 0E Chen, Xinjian, 03 Cheng, Wei-Chung, 0R Chowdhury, Aritra, 0Q Danforth, Theresa, 05 Diaz, Kristians, 0F Doi, Kunio, 11 Doyle, Scott, 05 Dyduch, Grzegorz, 0M Emmons, Tiffany, 0D Espig, Kathryn S., 0Y Eurén, Kristian, 0O Gabrani, Maria, 0P Gandomkar, Ziba, 02 Gann, Peter H., 0H Gao, Yi, 0K, 0W Ginley, Brandon, 0D, 0G Gray, Joe W., 0T Grimm, Oliver, 07 Gryanik, Alexander, 0B Gummeson, Anna, 0S Gupta, Sanchit, 0H Gurcan, Metin N., 0E, 0J Guzman, Grace, 04 Hasegawa, Madoka, 0Z Hashiguchi, Akinori, 0U Hashimoto, Emi, 0Z Hashizume, Makoto, 0Z Hasserjian, R. P., 0E Hedlund, Martin, 0O Hewitt, Stephen M., 08 Heyden, Anders, 0S Honda, Natsuki, 0U Hope, Tyna A., 0V Hoseini Alinodehi, S. Pourya, 06 Huang, Chao-Hui, 0A Ishikawa, Masahiro, 0U, 0Z Iwamoto, Chika, 0Z Jaworek-Korjakowska, Joanna, 0M Jiang, Zhiguo, 13 Jiménez del Toro, Oscar, 0O Johnson, Brett, 0T Kimpe, Tom R. L., 0Y Kłeczek, Paweł, 0M Kobayashi, Naoki, 0U, 0Z Komagata, Hideki, 0Z Koosha, Mohaddeseh, 06 Kopriva, Ivica, 03 Krappe, Sebastian, 0B, 0N Krzyzanowska, Agnieszka, 0S Kumar, Abhay, 0H Kumar, Neeraj, 0H Kurc, Tahsin, 0K Kwak, Jin Tae, 08 Lanciault, Christian, 0Y Lorsakul, Auranuch, 07 Louissaint, A., 0E Lozanski, G., 0E Lutnick, Brendon, 0I Ma, Yibing, 13 Margolin, Adam, 0T Mello-Thoms, Claudia, 02 Mochidome, Naoki, 0Z Müller, Henning, 0O Münzenmayer, Christian, 0B, 0N Navab, Nassir, 0F Niazi, M. Khalid Khan, 0J Nicolescu, Mircea, 06 Oda, Yoshinao, 0Z Ogura, Toshihiro, 11 Ohlsson, Mattias, 0S Ohuchida, Kenoki, 0Z Okajima, Mika, 11 Otálora, Sebastian, 0O Overgaard, Niels Christian, 0S Pennell, M., 0E Prisacari, Bogdan, 0P Racoceanu, Daniel, 0A, 0C Rönnquist, Peter, 0O Sade, Hadassah, 07 Safaei Naraghi, Zahra, 06 Sahiner, B., 0E Sakamoto, Michiie, 0U Saleheen, Firdous, 0R Saltz, Joel, 0K Salunke, Snehal Ulhas, 05 Santamaria-Pang, Alberto, 0Q Sarder, Pinaki, 0D, 0G, 0I Sasankan, Prabhu, 0D Sato, Mitsuru, 11 Schmidt, Günter, 09 Schonfeld, Dan, 10 Segal, Brahm H., 0D Senaras, C., 0E Sethi, Amit, 0H, 10 Sevinsky, Christopher J., 0Q Sha, Lingdao, 10 Shana’ah, A., 0E Shi, Huaqiang, 13 Shinoda, Kazuma, 0Z Sreedhar, Hari, 04 Stamminger, Marc, 0B, 0N Tadeusiewicz, Ryszard, 0M Tamashiro, Wataru, 11 Tannenbaum, Allen, 0K Tannich, Egbert, 0B Thibault, Guillaume, 0T Tolić, Dijana, 03 Tomaszewski, John E., 05, 0G, 0I Tsutsumi, Shoko, 11 Üner, Aysegül, 0N Urban, Constantin, 0D Varma, Vishal K., 04 Vega Harring, Suzana, 07 Verma, Ruchika, 0H Walsh, Michael J., 04 Wang, Fusheng, 0K Watanabe, Sumire, 0U Wegner, Christine, 0B Wen, Si, 0K Wild, Peter, 0P Wittenberg, Thomas, 0B, 0N Xie, Fengying, 13 Xthona, Albert, 0Y Yaffe, Martin J., 0V Yener, Bülent, 0Q Yigitsoy, Mehmet, 09 Yu, Xiaxia, 0K Zerhouni, Erwan, 0P Zhang, Haopeng, 13 Zhao, Tianhao, 0K Zhao, Yu, 13 Zheng, Yushan, 13 Zhong, Qing, 0P Zhou, Naiyun, 0K, 0W Zhu, Wei, 0K Conference CommitteeSymposium Chairs
Conference Chairs
Conference Program Committee
Session Chairs IntroductionThis is the fifth year of the Digital Pathology Conference that was introduced at SPIE’s Medical Imaging Symposium in Orlando, FL in 2013. Every year since that inaugural event we have seen increased interest in cell and tissue imaging which has made Digital Pathology one of the distinguished conferences at the Medical Imaging Symposium. The quality of the presented talks, posters, and the resulting papers, like in the previous years, continues to be outstanding. This is mainly thanks to our community of digital pathology image scientists and diagnosticians who submit some of their very best work to this conference. We are grateful for their good work. We are also thankful for all the hard work of our program committee, who carefully conducted a rigorous peer-review process to ensure that only top papers are selected for presentation at the meeting. The fifth Digital Pathology Conference took place on February 12 and 13 at the Renaissance SeaWorld, in Orlando, Florida, United States. A plenary talk was given on February 13th by Dr. Anant Madabhushi entitled "Image based risk score predictor: predicting disease aggressiveness using sub-visual cues from image data.” Dr. Madabhushi is an image scientist and one of the leaders in the field. Dr. Madabhushi discussed the motivation and rationale for developing image and fused data biomarkers in oncology. He illustrated the opportunity to mine both radiological and high-resolution histopathological images for data which supports both prognostic and predictive modeling in cancer. The audience was left with the clear message that there is critical information about the relationships amongst tumor cells and their host environment which can only be obtained through the use of quantitative image analytics. The keynote talk drew over 200 attendees from all the various conferences as part of the SPIE Medical imaging symposium. A total of 41 papers were presented during the course of the meeting in both oral and poster form. The sessions included Trends, Precision Medicine and Grading, Detection and Segmentation, Machine Learning, Emerging Technologies. We would like to acknowledge the excellent work in the following papers: Conference finalists of the Robert F. Wagner Best Student Paper Award for Digital Pathology (10140) Optimized color decomposition of localized whole slide images and convolutional neural network for intermediate prostate cancer classification Paper 10140-32 Student Author: Naiyun Zhou, Stony Brook Univ. (USA) Tissue classification of liver pathological tissue specimens image using spectral features Paper 10140-36 Student Author: Emi Hashimoto, Saitama Medical University, Saitama (Japan) Poster Awards Cum Laude Poster Award Panning artifacts in digital pathology images, Ali R. N. Avanaki, Barco, Inc. (USA) [10140-34] Honorable Mention Poster Award Topological descriptors for quantitative prostate cancer morphology analysis, Peter J. Lawson, Tulane Univ. (USA); Eric Berry, Montana State Univ. (USA); J. Quincy Brown, Tulane Univ. (USA); Brittany T. Fasy, Montana State Univ. (USA); Carola Wenk, Tulane Univ. (USA) [10140-33] The continued success of the Digital Pathology conference is in no small part due to the outstanding efforts of the program committee who carefully constructed the program, the Conference Chairs Drs. Berkman Sahiner and Leonard Berliner, and SPIE management who kindly guided us through all the many steps of the program organization. Next year the Medical Imaging meeting will take place in Houston, TX. We look forward to seeing you there for another successful conference. Metin N. Gurcan John E. Tomaszewski 2017 Medical Imaging Award RecipientsRobert F. Wagner Best Student Paper Award Robert F. Wagner was an active scientist in the SPIE Medical Imaging meeting, starting with the first meeting in 1972 and continuing throughout his career. He ensured that the BRH, and subsequently the CDRH, was a sponsor for the early and subsequent Medical Imaging meetings, helping to launch and ensure the historical success of the meeting. The Robert F. Wagner All-Conference Best Student Paper Award I (established 2014) is acknowledgment of his many important contributions to the Medical Imaging meeting and his many important advances to the field of medical imaging. This award is cosponsored by: First Place: Direct measurement of Lubberts effect in CsI:Tl scintillators using single x-ray photon imaging (10132-8) A. Howansky, A. R. Lubinsky, Stony Brook Univ. (United States); S. K. Ghose, Brookhaven National Lab. (United States); K. Suzuki, Hamamatsu Photonics K.K. (Japan); W. Zhao, Stony Brook Univ. (United States) Second Place: Evaluation of a high-resolution patient-specific model of the electrically stimulated cochlea (10135-21) A. Cakir, Vanderbilt Univ. (United States); R. T. Dwyer, Vanderbilt Univ. Medical Ctr. (United States); J. H. Noble, Vanderbilt Univ. (United States) |
