Portable fiber-optic taper coupled optical microscopy platform

Weiming Wang; Yan Yu; Hui Huang; Jinping Ou

doi:10.1117/12.2258587

17 April 2017 Portable fiber-optic taper coupled optical microscopy platform

Weiming Wang, Yan Yu, Hui Huang, Jinping Ou

Proceedings Volume 10167, Nanosensors, Biosensors, Info-Tech Sensors and 3D Systems 2017; 101671S (2017) https://doi.org/10.1117/12.2258587
Event: SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, 2017, Portland, Oregon, United States

Abstract

The optical fiber taper coupled with CMOS has advantages of high sensitivity, compact structure and low distortion in the imaging platform. So it is widely used in low light, high speed and X-ray imaging systems. In the meanwhile, the peculiarity of the coupled structure can meet the needs of the demand in microscopy imaging. Toward this end, we developed a microscopic imaging platform based on the coupling of cellphone camera module and fiber optic taper for the measurement of the human blood samples and ascaris lumbricoides. The platform, weighing 70 grams, is based on the existing camera module of the smartphone and a fiber-optic array which providing a magnification factor of ~6x.The top facet of the taper, on which samples are placed, serves as an irregular sampling grid for contact imaging. The magnified images of the sample, located on the bottom facet of the fiber, are then projected onto the CMOS sensor. This paper introduces the portable medical imaging system based on the optical fiber coupling with CMOS, and theoretically analyzes the feasibility of the system. The image data and process results either can be stored on the memory or transmitted to the remote medical institutions for the telemedicine. We validate the performance of this cell-phone based microscopy platform using human blood samples and test target, achieving comparable results to a standard bench-top microscope.

Citation Download Citation

Weiming Wang, Yan Yu, Hui Huang, and Jinping Ou "Portable fiber-optic taper coupled optical microscopy platform", Proc. SPIE 10167, Nanosensors, Biosensors, Info-Tech Sensors and 3D Systems 2017, 101671S (17 April 2017); https://doi.org/10.1117/12.2258587

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