Biosensing using long-range surface plasmon waveguides

Oleksiy Krupin; Maryam Khodami; Hui Fan; Wei Ru Wong; Faisal Rafiq Mahamd Adikan; Pierre Berini

doi:10.1117/12.2268976

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17 May 2017 Biosensing using long-range surface plasmon waveguides

Oleksiy Krupin, Maryam Khodami, Hui Fan, Wei Ru Wong, Faisal Rafiq Mahamd Adikan, Pierre Berini

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Proceedings Volume 10242, Integrated Optics: Physics and Simulations III; 1024203 (2017) https://doi.org/10.1117/12.2268976
Event: SPIE Optics + Optoelectronics, 2017, Prague, Czech Republic

Abstract

Long-range surface plasmon waveguides, and their application to various transducer architectures for amplitude- or phase-sensitive biosensing, are discussed. Straight and Y-junction waveguides are used for direct intensity-based detection, whereas Bragg gratings and single-, dual- and triple-output Mach Zehnder interferometers are used for phasebased detection. In either case, multiple-output biosensors which provide means for referencing are very useful to eliminate common perturbations and drift. Application of the biosensors to disease detection in complex fluids is discussed. Application to biomolecular interaction analysis and kinetics extraction is also discussed.

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Oleksiy Krupin, Maryam Khodami, Hui Fan, Wei Ru Wong, Faisal Rafiq Mahamd Adikan, and Pierre Berini "Biosensing using long-range surface plasmon waveguides", Proc. SPIE 10242, Integrated Optics: Physics and Simulations III, 1024203 (17 May 2017); https://doi.org/10.1117/12.2268976

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