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26 June 2017 Hybrid model of arm for analysis of regional blood oxygenation in non-invasive optical diagnostics
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The paper presents a new comprehensive approach to modeling and analysis of processes occurring during the blood flow in the arm‟s small vessels as well as non-invasive measurement method of mixed venous oxygen saturation. During the work, a meta-analysis of available physiological data was performed and based on its result a hybrid model of forearm vascular tree was proposed. The model, in its structure, takes into account a classical nonlinear hydro-electric analogy in conjunction with light-tissue interaction. Several geometries of arm vascular tree obtained from magnetic resonance angiography (MRA) image were analyzed which allowed to proposed the structure of electrical analog network. Proposed model allows to simulate the behavior of forearm blood flow from the vascular tree mechanics point of view, as well as effects of the impact of cuff and vessel wall mechanics on the recorded photoplethysmographic signals. In particular, it allows to analyze the reaction and anatomical effects in small vessels and microcirculation caused by occlusive maneuver in selected techniques, what was of particular interest to authors and motivation to undertake research in this area. Preliminary studies using proposed model showed that inappropriate selection of occlusion maneuver parameters (e.g. occlusion time, cuff pressure etc.), cause dangerous turbulence of blood flow in the venous section of the vascular tree.
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Sylwester Nowocień and Janusz Mroczka "Hybrid model of arm for analysis of regional blood oxygenation in non-invasive optical diagnostics", Proc. SPIE 10330, Modeling Aspects in Optical Metrology VI, 103301A (26 June 2017);

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