Cherenkov imaging for Total Skin Electron Therapy (TSET)

Yunhe Xie; Heather Petroccia; Amit Maity; Tianshun Miao; Yihua Zhu; Petr Bruza; Brian W. Pogue; Jacqueline M. Andreozzi; John P. Plastaras; Lei Dong; Timothy C. Zhu

doi:10.1117/12.2291441

5 March 2018 Cherenkov imaging for Total Skin Electron Therapy (TSET)

Yunhe Xie, Heather Petroccia, Amit Maity, Tianshun Miao, Yihua Zhu, Petr Bruza, Brian W. Pogue, Jacqueline M. Andreozzi, John P. Plastaras, Lei Dong, Timothy C. Zhu

Author Affiliations +

Proceedings Volume 10478, Molecular-Guided Surgery: Molecules, Devices, and Applications IV; 1047816 (2018) https://doi.org/10.1117/12.2291441
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Total Skin Electron Therapy (TSET) utilizes high-energy electrons to treat cancers on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high-energy electron beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to evaluate the dose uniformity on the surface of the patient in real-time. Each patient was also monitored during TSET via in-vivo detectors (IVD) in nine locations. Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed, and the viability of the system to provide clinical feedback was established.

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Yunhe Xie, Heather Petroccia, Amit Maity, Tianshun Miao, Yihua Zhu, Petr Bruza, Brian W. Pogue, Jacqueline M. Andreozzi, John P. Plastaras, Lei Dong, and Timothy C. Zhu "Cherenkov imaging for Total Skin Electron Therapy (TSET)", Proc. SPIE 10478, Molecular-Guided Surgery: Molecules, Devices, and Applications IV, 1047816 (5 March 2018); https://doi.org/10.1117/12.2291441

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