Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

Christian Rosenberg Petersen; Nikola Prtljaga; Mark Farries; Jon Ward; Bruce Napier; Gavin Rhys Lloyd; Jayakrupakar Nallala; Nick Stone; Ole Bang

doi:10.1117/12.2288541

19 February 2018 Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

Christian Rosenberg Petersen, Nikola Prtljaga, Mark Farries, Jon Ward, Bruce Napier, Gavin Rhys Lloyd, Jayakrupakar Nallala, Nick Stone, Ole Bang

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Proceedings Volume 10489, Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis; 1048905 (2018) https://doi.org/10.1117/12.2288541
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

We present the first demonstration of mid-infrared spectroscopic imaging of human tissue using a fiber-coupled supercontinuum source spanning from 2-7.5 μm. The supercontinuum was generated in a tapered large mode area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for good imaging properties. Tissue imaging was demonstrated in transmission by raster scanning over a sub-mm region of paraffinized colon tissue on CaF₂ substrate, and the signal was measured using a fiber-coupled grating spectrometer. This demonstration has shown that we can distinguish between epithelial and surrounding connective tissues within a paraffinized section of colon tissue by imaging at discrete wavelengths related to distinct chemical absorption features.

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Christian Rosenberg Petersen, Nikola Prtljaga, Mark Farries, Jon Ward, Bruce Napier, Gavin Rhys Lloyd, Jayakrupakar Nallala, Nick Stone, and Ole Bang "Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber", Proc. SPIE 10489, Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis, 1048905 (19 February 2018); https://doi.org/10.1117/12.2288541

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KEYWORDS

Spectroscopy

Mid-IR

Imaging spectroscopy

Imaging systems

Tissues

Absorption

FT-IR spectroscopy

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