Novel liposomal technology applied in esophageal cancer treatment

Chia-Hsien Yeh; Yei-San Hsieh; Pei-wen Yang; Leaf Huang; Yih-Chih Hsu

doi:10.1117/12.2291494

19 February 2018 Novel liposomal technology applied in esophageal cancer treatment

Chia-Hsien Yeh, Yei-San Hsieh, Pei-wen Yang, Leaf Huang, Yih-Chih Hsu

Proceedings Volume 10495, Biophotonics and Immune Responses XIII; 104950D (2018) https://doi.org/10.1117/12.2291494
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Cisplatin (CDDP) has been commonly used as a chemotherapeutic drug, mainly used for the treatment of malignant epithelial cell tumors. We have developed a new method based on innovative lipid calcium phosphate, which encapsulated hydrophobic drugs to form liposomal nanoparticles. Esophageal cancer xenograft model was used to investigate the efficacy of liposomal nanoparticles. and it showed good therapeutic efficacy with lower side effects. Liposomal nanoparticles exhibited a better therapeutic effect than that of conventional CDDP.

Citation Download Citation

Chia-Hsien Yeh, Yei-San Hsieh, Pei-wen Yang, Leaf Huang, and Yih-Chih Hsu "Novel liposomal technology applied in esophageal cancer treatment", Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 104950D (19 February 2018); https://doi.org/10.1117/12.2291494

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