Far-field wide-field label-free nanoscale imaging based on full-angle evanescent wave illumination (Conference Presentation)

Qing Yang

doi:10.1117/12.2290233

14 March 2018 Far-field wide-field label-free nanoscale imaging based on full-angle evanescent wave illumination (Conference Presentation)

Qing Yang

Author Affiliations +

Proceedings Volume 10540, Quantum Sensing and Nano Electronics and Photonics XV; 105400R (2018) https://doi.org/10.1117/12.2290233
Event: SPIE OPTO, 2018, San Francisco, California, United States

Abstract

We demonstrate a novel active far-field wide-field label-free nano-imaging with high signal-to-noise ratio based on the nanoscale light source, pioneering in utilizing a combination of spatial frequency shift and Stokes frequency shift. Ring shape or polygonal shape nanoscale light sources emit photoluminescence and the light is coupled to a underneath subwavelength film waveguide to produce omnidirectional illuminating evanescent waves to shift high spatial frequencies for the far-field, label-free, 2D subdiffraction imaging. The photoluminescence of the nanostructure enables high-efficiency evanescent wave coupling in a large area for the low-noise wide-field imaging. The field of view is one order of magnitude improved from the previously reported far-field and full-field method. This approach’s versatility has been demonstrated by imaging integrated chips, Blu-ray DVDs, biological cells and various subwavelength 2D patterns. The configuration-----a special NW assisted slide-----is cost-effective, quite compatible with the standard microscope and can conveniently give super resolvability to conventional microscopy as a compact module. This work is significant for physics, materials, biology, chemistry, and other areas that need nanoscale visualization.

Conference Presentation

Citation Download Citation

Qing Yang "Far-field wide-field label-free nanoscale imaging based on full-angle evanescent wave illumination (Conference Presentation)", Proc. SPIE 10540, Quantum Sensing and Nano Electronics and Photonics XV, 105400R (14 March 2018); https://doi.org/10.1117/12.2290233

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