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Virtual reality (VR) training simulators of liver needle insertion in the hepatic area of breathing virtual patients often need 4D image data acquisitions as a prerequisite. Here, first a population-based breathing virtual patient 4D atlas is built and second the requirement of a dose-relevant or expensive acquisition of a 4D CT or MRI data set for a new patient can be mitigated by warping the mean atlas motion. The breakthrough contribution of this work is the construction and reuse of population-based, learned 4D motion models.
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Andre Mastmeyer, Matthias Wilms, Heinz Handels, "Population-based respiratory 4D motion atlas construction and its application for VR simulations of liver punctures," Proc. SPIE 10574, Medical Imaging 2018: Image Processing, 1057417 (2 March 2018); https://doi.org/10.1117/12.2293092