Dosimetry Of Plaque Ablation Using Thermal And Thermal-Optical Probe Systems

Ross G. Hoffman; George S. Abela; Stephan E. Friedl; Bahram Hojjatie; Gerald R. Barbeau

doi:10.1117/12.952111

15 June 1989 Dosimetry Of Plaque Ablation Using Thermal And Thermal-Optical Probe Systems

Ross G. Hoffman, George S. Abela, Stephan E. Friedl, Bahram Hojjatie, Gerald R. Barbeau

Proceedings Volume 1067, Optical Fibers in Medicine IV; (1989) https://doi.org/10.1117/12.952111
Event: OE/LASE '89, 1989, Los Angeles, CA, United States

Abstract

The characterization of laser energy dosages for plaque vaporization using laser thermal-activated probe systems may provide a method to enhance efficiency of vaporization and limit excess thermal tissue damage. This study was conducted using two probe systems currently available for human use; the laser thermal probe or "hot-tip" and the laser thermal-optical probe system or "hybrid". Probe temperature was obtained using a K-type thermocouple. Atherosclerotic human cadaveric plaque was irradiated in air and in saline medium. In air, the volume of plaque vaporized rose with increasing power and exposure time for both probe systems. The mean volume of vaporized plaque at all energy levels was significantly higher for the thermal-optical system compared to the laser thermal system [2.9 μl vs 2.2 μl respectively; p < 0.01]. Also, with both probe systems, comparison of volume of tissue vaporized at the same energy levels showed that below 80 joules of total energy delivered, increasing the power parameter was more efficient in plaque vaporization than increasing the exposure time. Finally, the volume of plaque vaporized per °C was greater for the thermal-optical system as compared to the thermal system [0.0050 vs 0.0036 μl per °C ; p < 0.01]. Under saline medium, the laser thermal probe initiate vaporization only after 60 joules (J) versus 30 J for the thermal-optical system. Additionally, histologic studies showed that deeper plaque penetration occurred with the thermal-optical system compared to the pure thermal system. The results of this study suggest that the laser thermal-optical system is more efficient than the laser thermal system for plaque vaporization.

Citation Download Citation

Ross G. Hoffman, George S. Abela, Stephan E. Friedl, Bahram Hojjatie, and Gerald R. Barbeau "Dosimetry Of Plaque Ablation Using Thermal And Thermal-Optical Probe Systems", Proc. SPIE 1067, Optical Fibers in Medicine IV, (15 June 1989); https://doi.org/10.1117/12.952111

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