Application of microstructural optical waveguides with hollow core for enzyme immunoassay

Pavel S. Pidenko; Sergei A. Pidenko; Natalia A. Burmistrova; Andrei A. Shuvalov; Anastasiya A. Chibrova; Yulia S. Skibina; Irina Y. Goryacheva

doi:10.1117/12.2314402

26 April 2018 Application of microstructural optical waveguides with hollow core for enzyme immunoassay

Pavel S. Pidenko, Sergei A. Pidenko, Natalia A. Burmistrova, Andrei A. Shuvalov, Anastasiya A. Chibrova, Yulia S. Skibina, Irina Y. Goryacheva

Author Affiliations +

Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX; 107161V (2018) https://doi.org/10.1117/12.2314402
Event: Saratov Fall Meeting 2017, 2017, Saratov, Russian Federation

Abstract

Microstructural optical waveguides with the hollow core are actively studied as a promising support for heterogeneous immunoassay in development of new optical biosensor elements for medicine and biology. Overcoming of the limitations associated with the low sorption capacity of glass used for the waveguides production is a crucial step for this assay format. In this work the possibility of silanization of microstructural optical waveguides with the hollow core using (3-glycidyloxypropyl) trimethoxysilane and their further application to enzymatic immunoassay was studied.

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Pavel S. Pidenko, Sergei A. Pidenko, Natalia A. Burmistrova, Andrei A. Shuvalov, Anastasiya A. Chibrova, Yulia S. Skibina, and Irina Y. Goryacheva "Application of microstructural optical waveguides with hollow core for enzyme immunoassay", Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107161V (26 April 2018); https://doi.org/10.1117/12.2314402

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