Spectroscopic image criteria for the selection of patients with ovarian cancer for further molecular genetic studies

O. P. Peresunko; M. S. Gavrylyak; S. B. Yermolenko

doi:10.1117/12.2320447

17 September 2018 Spectroscopic image criteria for the selection of patients with ovarian cancer for further molecular genetic studies

O. P. Peresunko, M. S. Gavrylyak, S. B. Yermolenko

Author Affiliations +

Proceedings Volume 10752, Applications of Digital Image Processing XLI; 107522B (2018) https://doi.org/10.1117/12.2320447
Event: SPIE Optical Engineering + Applications, 2018, San Diego, California, United States

Abstract

The article is devoted to the substantiation of the selection of patients with ovarian cancer (OC) for the purpose of conducting expensive molecular genetic studies on genotyping, namely the identification of gene of hereditary predisposition of OC (BRCA1 and BRCA2). The proposed method makes it possible at the first stage to find among all patients with ovarian the proposed individuals whose further molecular genetic studies will objectively confirm the diagnosis of hereditary cancer (by genotyping on (BRCA I and II), which significantly reduces the cost of these studies in the population. A preliminary data show that the optical method of infrared plasma spectroscopy of patients with ovarian cancer patients needs further research as a test screening method for the diagnosis of hereditary ovarian cancer as a preliminary selection of patients for molecular genetic studies (BRCA I and II).

Citation Download Citation

O. P. Peresunko, M. S. Gavrylyak, and S. B. Yermolenko "Spectroscopic image criteria for the selection of patients with ovarian cancer for further molecular genetic studies", Proc. SPIE 10752, Applications of Digital Image Processing XLI, 107522B (17 September 2018); https://doi.org/10.1117/12.2320447

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