Animal models in guided bone regeneration using photobiomodulation: general aspects and particularities influencing the studies outcome - a review

Ruxandra Luca; Carmen Darinca Todea M.D.; George D. Constantin; Daliana Mocuta; Roxana Munteanu

doi:10.1117/12.2285172

10 August 2018 Animal models in guided bone regeneration using photobiomodulation: general aspects and particularities influencing the studies outcome - a review

Ruxandra Luca, Carmen Darinca Todea M.D., George D. Constantin, Daliana Mocuta, Roxana Munteanu

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Proceedings Volume 10831, Seventh International Conference on Lasers in Medicine; 108310A (2018) https://doi.org/10.1117/12.2285172
Event: Seventh International Conference on Lasers in Medicine, 2017, Timisoara, Romania

Abstract

The healing process of bone defects is time consuming, and new bone generation takes place slowly because of decreased blood supply to the fracture site and insufficiency of calcium and phosphorus to strengthen and harden new bone. In addition, large defects, also known as critical bone defects, may not heal spontaneously and lead to nonunion prognosis due to the size of defects or unstable biomechanical properties, unfavorable wound environment, suboptimal surgical technique, metabolic factors, hormones, nutrition, and applied stress.

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Ruxandra Luca, Carmen Darinca Todea M.D., George D. Constantin, Daliana Mocuta, and Roxana Munteanu "Animal models in guided bone regeneration using photobiomodulation: general aspects and particularities influencing the studies outcome - a review", Proc. SPIE 10831, Seventh International Conference on Lasers in Medicine, 108310A (10 August 2018); https://doi.org/10.1117/12.2285172

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KEYWORDS

Bone

Animal model studies

Calcium

Laser therapeutics

In vivo imaging

Proteins

Tissues

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