CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 10854 > Article
Presentation
4 March 2019 Transnasal introduction catheter, a new platform for imaging and biopsying the gastrointestinal (GI) tract (Conference Presentation)
Hamid Farrokhi, Jing Dong, David O. Otuya, Yogesh Verma, Sarah K. Zemlok, Aditya Kumar, Rachel E. Shore, Sarah L. L. Giddings, Nitasha G. M. Bhat, Omair Shakil, Catriona N. Grant, Norman Nishioka, Mireille Rosenberg, Christopher Damman, Guillermo J. Tearney
Author Affiliations +
Proceedings Volume 10854, Endoscopic Microscopy XIV; 108540L (2019) https://doi.org/10.1117/12.2510381
Event: SPIE BiOS, 2019, San Francisco, California, United States
Abstract
Upper endoscopy is a standard technique for imaging, sampling, and treating gastrointestinal tissue. Endoscopy is frequently requiring the subjects who undergo the procedure be consciously sedated. Sedation necessitates that the endoscopy procedure be conducted in a specialized setting to mitigate complications should they arise. Endoscopy is further problematic for infants and young children (aged 0-24 months) who sometimes need to be anesthetized. These issues motivate alternative methods for upper gastrointestinal tract visualization and biopsy that do not require conscious sedation/anesthesia. To address this need, we have developed a double lumen 6.5 Fr transnasal introduction catheter (TNIC). During transnasal insertion, real-time OCT imaging provides confirmation of the anatomical location of the device. Once in the stomach, a safe and high-density liquid metal fills a balloon at the distal tip of the TNIC, allowing it to passively transit through stomach into the small intestine. Once properly positioned, OCT-guided instruments for imaging and biopsy can be inserted through main lumen of the TNIC, performing many of the functions of conventional endoscopy and advanced endomicroscopy. To test the feasibility of the TNIC, we conducted a clinical study using the first version of the device in 4 unsedated normal volunteers. Results showed detailed OCT endomicroscopy images of the esophagi and duodena. These results suggest that TNIC may be an effective, less invasive method for the diagnosis of upper GI tract conditions.
Conference Presentation
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Hamid Farrokhi, Jing Dong, David O. Otuya, Yogesh Verma, Sarah K. Zemlok, Aditya Kumar, Rachel E. Shore, Sarah L. L. Giddings, Nitasha G. M. Bhat, Omair Shakil, Catriona N. Grant, Norman Nishioka, Mireille Rosenberg, Christopher Damman, and Guillermo J. Tearney "Transnasal introduction catheter, a new platform for imaging and biopsying the gastrointestinal (GI) tract (Conference Presentation)", Proc. SPIE 10854, Endoscopic Microscopy XIV, 108540L (4 March 2019); https://doi.org/10.1117/12.2510381
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Endoscopy
Biopsy
Endomicroscopy
Optical coherence tomography
Stomach
Francium
Liquids
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top