Long-term photoacoustic brain imaging in a freely moving rat

Qian Chen; Lei Xi

doi:10.1117/12.2507790

1 March 2019 Long-term photoacoustic brain imaging in a freely moving rat

Qian Chen, Lei Xi

Proceedings Volume 10865, Neural Imaging and Sensing 2019; 108650W (2019) https://doi.org/10.1117/12.2507790
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Photoacoustic microscopy (PAM) is an emerging technique extensively used to study brain activities. However, limited by the size and performance of optical/acoustic scanners, existing ORPAMs are still bulky, heavy, and suffer from low imaging quality/speed. Here, we develop a wearable ORPAM probe featuring small, light, fast, and cellular imaging capability. To evaluate the probe, we monitored the cerebral vascular network within two hours and demonstrated that the microscope was stable enough to study long-term brain hemodynamics in a freely moving rat.

Conference Presentation

Citation Download Citation

Qian Chen and Lei Xi "Long-term photoacoustic brain imaging in a freely moving rat", Proc. SPIE 10865, Neural Imaging and Sensing 2019, 108650W (1 March 2019); https://doi.org/10.1117/12.2507790

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available