Translator Disclaimer
Paper
1 March 2019 A multi spectral hand-held spatial frequency domain imaging system for imaging human colorectal cancer
Author Affiliations +
Abstract
A multi-spectral, portable, hand-held LED based spatial frequency domain imaging system was used for ex vivo imaging pretreatment and post treatment human colon and rectal tissues. Freshly excised human colon and rectal tissue samples were imaged with the hand-held SFDI probe with 9 wavelengths extending from visible to NIR (660-950 nm). Important tumor biomarkers such as hemoglobin, scatter amplitude, scatter spectral slope, water and lipid content were quantitatively extracted from the SFDI absorption and scattering images. Significant differences were observed between the absorption as well as scattering distribution of normal, tumor and polyp tissue as well as between pretreated and post-treated tumors.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yifeng Zeng, Shuying Li, Mohsen Erfanzadeh, Sreyankar Nandy, William Chapman Jr., Zahra Alipour, Heba Abdelal, Deyali Chatterjee, Matthew Mutch, and Quing Zhu "A multi spectral hand-held spatial frequency domain imaging system for imaging human colorectal cancer", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 108740T (1 March 2019); https://doi.org/10.1117/12.2510320
PROCEEDINGS
3 PAGES


SHARE
Advertisement
Advertisement
Back to Top