In silico investigation of near-infrared light propagation in the joints of the human hand

David Cohen; Mamadou Diop

doi:10.1117/12.2508933

1 March 2019 In silico investigation of near-infrared light propagation in the joints of the human hand

David Cohen, Mamadou Diop

Proceedings Volume 10874, Optical Tomography and Spectroscopy of Tissue XIII; 1087427 (2019) https://doi.org/10.1117/12.2508933
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Optical tomography imaging (OTI) of joints is challenging since light is highly scattered by tissue, leading to poor spatial resolution. Image quality can be improved by early-photons imaging; however, the image reconstruction will require more advanced forward models than the classic methods based on the diffusion approximation. We aim to use Monte-Carlo simulations as forward model for early-photons OTI. To test the feasibility, DICOM images of the hand of an adult male, obtained from an MRI, were imported into 3DSlicer where the bones and soft tissue were segmented. The MATLAB-based toolbox Iso2Mesh was used to generate a 3D volumetric mesh of the segmented image. Typical optical properties (i.e., absorption coefficient, scattering coefficient, anisotropic index, and refractive index) of bone and soft tissue were assigned to each node of the 3D mesh and light propagation was simulated using the Mesh-based MonteCarlo (MMC) toolbox. Our results show that our approach can reliable model propagation of early-photons in the highly heterogeneous human wrist.

Citation Download Citation

David Cohen and Mamadou Diop "In silico investigation of near-infrared light propagation in the joints of the human hand ", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 1087427 (1 March 2019); https://doi.org/10.1117/12.2508933

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available