Quantifying lens elastic properties with optical coherence elastography as a function of intraocular pressure

Chen Wu; Hongqiu Zhang; Manmohan Singh; Salavat R. Aglyamov; Kirill V. Larin

doi:10.1117/12.2510225

21 February 2019 Quantifying lens elastic properties with optical coherence elastography as a function of intraocular pressure

Chen Wu, Hongqiu Zhang, Manmohan Singh, Salavat R. Aglyamov, Kirill V. Larin

Author Affiliations +

Proceedings Volume 10880, Optical Elastography and Tissue Biomechanics VI; 108801P (2019) https://doi.org/10.1117/12.2510225
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Normal intraocular pressure (IOP) is crucial for proper maintaining of eye-globe geometry, ocular tissue health, and visual acuity. An elevated IOP is associated with diseases such as glaucoma and uveitis. While the effects of an elevated IOP on the delicate tissues of the optic nerve head and retina are well-studied, the changes in lenticular biomechanical properties as a function of IOP are not as clear. Moreover, changes in lenticular biomechanical properties have been implicated in conditions and diseases such as presbyopia and cataract. However, measuring the biomechanical properties of the lens as it sits inside the eye-globe is a challenge, but it is necessary to correctly understand the interplay between lenticular biomechanical properties and IOP. In this work, we utilized optical coherence elastography (OCE) to measure the biomechanical properties of the porcine lens in situ.

Citation Download Citation

Chen Wu, Hongqiu Zhang, Manmohan Singh, Salavat R. Aglyamov, and Kirill V. Larin "Quantifying lens elastic properties with optical coherence elastography as a function of intraocular pressure", Proc. SPIE 10880, Optical Elastography and Tissue Biomechanics VI, 108801P (21 February 2019); https://doi.org/10.1117/12.2510225

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