CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 10894 > Article
Presentation
4 March 2019 Development of innovative plasmonic nanostructures for vibrational biosensing
J. Popp, Dana Cialla-May
Author Affiliations +
Proceedings Volume 10894, Plasmonics in Biology and Medicine XVI; 1089402 (2019) https://doi.org/10.1117/12.2507207
Event: SPIE BiOS, 2019, San Francisco, California, United States
Abstract
In order to allow for a molecular specific as well as trace level sensitive detection in biosensing, vibrational spectroscopy is applied in combination with plasmonic active materials. Within this contribution, we report on the surface-enhanced Raman spectroscopy (SERS) technique, the fabrication of powerful SERS substrates and finally illustrate the potential in biosensing. Mannose-modified SERS tags are applied to be taken up by macrophages in a large amount which serves as a model for the detection of vulnerable atherosclerotic plaques in an early stage. Moreover, to allow for an improved quantification SERS active surfaces are equipped with an internal standard. Finally, a newly developed fabrication strategy of SERS substrate templates will be introduced forming 3D hierarchical nanostructures by metastable state assisted atomic layer deposition. Thus, a detailed overview on innovative plasmonic nanostructures for biosensing developed in our labs is given.
Conference Presentation
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
J. Popp and Dana Cialla-May "Development of innovative plasmonic nanostructures for vibrational biosensing", Proc. SPIE 10894, Plasmonics in Biology and Medicine XVI, 1089402 (4 March 2019); https://doi.org/10.1117/12.2507207
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Plasmonics
Infrared spectroscopy
Biosensing
Nanostructures
Absorption
Infrared sensors
Lab on a chip
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top