Experimental validation of a multi-step material decomposition method for spectral CT

Nathaniel R. Fredette; Stefano Vespucci; Mini Das

doi:10.1117/12.2513503

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3 April 2019 Experimental validation of a multi-step material decomposition method for spectral CT

Nathaniel R. Fredette, Stefano Vespucci, Mini Das

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Proceedings Volume 10948, Medical Imaging 2019: Physics of Medical Imaging; 109482T (2019) https://doi.org/10.1117/12.2513503
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

Recently, we proposed a multi-step material decomposition method for spectral CT where the decomposition is solved in a series of steps each separating one new material from the original attenuation data. Until now, this method has only been tested using numerical simulations of multi-material digital phantoms. Here we present the initial results of the multistep method applied to experimental data acquired in our laboratory using a Medipix 3RX detector with a silicon senor. The decomposition of CT images of a 3-material phantom is demonstrated. The materials studied here are gadolinium (Gd), iodine (I) and acrylonitrile butadiene styrene (ABS) plastic. The results show qualitative and quantitative improvement in separation accuracy as the worst-case percent error in one selected slice is reduced by 51.7% when using our new method in comparison to a conventional single-step material decomposition.

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Nathaniel R. Fredette, Stefano Vespucci, and Mini Das "Experimental validation of a multi-step material decomposition method for spectral CT", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109482T (3 April 2019); https://doi.org/10.1117/12.2513503

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