Investigation of necessary conditions for imaging cell analysis using EIT

Christian Gibas; Birgyl Veckollari; Gregor Schulte; Mareike Müller; Rainer Brück; Holger Schönherr

doi:10.1117/12.2512404

15 March 2019 Investigation of necessary conditions for imaging cell analysis using EIT

Christian Gibas, Birgyl Veckollari, Gregor Schulte, Mareike Müller, Rainer Brück, Holger Schönherr

Author Affiliations +

Proceedings Volume 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging; 109532B (2019) https://doi.org/10.1117/12.2512404
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

Electrical Impedance Tomography (EIT) is a method used to record the impedance distribution within a target. The best-known application of EIT is lung diagnostics using imaging algorithms. However, apart from this, there are individual research projects dealing with imaging analysis at the cellular level. For example, cell analysis using EIT can help to distinguish diseased cells from healthy cells. To achieve this goal, an existing EIT system was combined with a new EIT chip in a first step. This chip allows analysis in very small dimensions. Various parameters such as the diameter of the measuring environment, the necessary conductive solutions or the measuring methods used were varied and evaluated. In a next step, various image reconstructions were carried out using data acquired with C. elegans.

Citation Download Citation

Christian Gibas, Birgyl Veckollari, Gregor Schulte, Mareike Müller, Rainer Brück, and Holger Schönherr "Investigation of necessary conditions for imaging cell analysis using EIT", Proc. SPIE 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging, 109532B (15 March 2019); https://doi.org/10.1117/12.2512404

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