Pilot studies of age-related changes in blood perfusion in two different types of skin

Yulia I. Loktionova; Elena V. Zharkikh; Igor O. Kozlov; Evgeny A. Zherebtsov; Svetlana A. Bryanskaya; Angelina I. Zherebtsova; Victor V. Sidorov; Sergei G. Sokolovski; Andrey V. Dunaev; Edik U. Rafailov

doi:10.1117/12.2522968

3 June 2019 Pilot studies of age-related changes in blood perfusion in two different types of skin

Yulia I. Loktionova, Elena V. Zharkikh, Igor O. Kozlov, Evgeny A. Zherebtsov, Svetlana A. Bryanskaya, Angelina I. Zherebtsova, Victor V. Sidorov, Sergei G. Sokolovski, Andrey V. Dunaev, Edik U. Rafailov

Author Affiliations +

Proceedings Volume 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine; 110650S (2019) https://doi.org/10.1117/12.2522968
Event: International Symposium on Optics and Biophotonics VI: Saratov Fall Meeting 2018, 2018, Saratov, Russian Federation

Abstract

Laser Doppler flowmetry (LDF) was utilized to assess age-related changes in the blood microcirculation at the skin sites with different morphology and regulation. The LDF signals obtained from the glabrous skin of the middle finger pad and nonglabrous skin on the dorsal wrist surface were analyzed. Statistically higher baseline perfusion was observed in the zone with glabrous skin in the older group of volunteers compared to younger participants. Observed site-specific and age-related differences in perfusion can be used in the future experimental design for the studies of the blood microcirculation system in patients with different pathologies.

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Yulia I. Loktionova, Elena V. Zharkikh, Igor O. Kozlov, Evgeny A. Zherebtsov, Svetlana A. Bryanskaya, Angelina I. Zherebtsova, Victor V. Sidorov, Sergei G. Sokolovski, Andrey V. Dunaev, and Edik U. Rafailov "Pilot studies of age-related changes in blood perfusion in two different types of skin", Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 110650S (3 June 2019); https://doi.org/10.1117/12.2522968

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