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7 August 2019 Determination of in-vivo tissue optical properties for anal photodynamic therapy
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Proceedings Volume 11070, 17th International Photodynamic Association World Congress; 11070BI (2019) https://doi.org/10.1117/12.2525624
Event: 17th International Photodynamic Association World Congress, 2019, Cambridge, Massachusetts, United States
Abstract
Determination of in-vivo tissue optical properties for anal photodynamic therapy (PDT) is challenging due to the light integrating-sphere effect in an enclosed cylindrical cavity. We developed a model for optical properties determination for anal PDT from measurements of light fluence rate inside a cylindrical cavity submerged in tissue-mimicking liquid phantoms. Measurements are performed in a set of phantoms with known optical properties (μa = 0.1-0.9 cm-1) and (μs’ = 5.5-16.5 cm-1) and the primary and scatter light fluence rates are determined. We developed a forward empirical model to relate scatter light fluence rate measured in an enclosed cylindrical geometry to the surrounding tissue optical properties in tissue-simulating liquid phantoms.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Andrew C. Li, Yi Hong Ong, Andreea Dimofte, Theresa M. Busch, and Timothy C. Zhu "Determination of in-vivo tissue optical properties for anal photodynamic therapy", Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 11070BI (7 August 2019); https://doi.org/10.1117/12.2525624
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