CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11074 > Article
Paper
11 July 2019 Effects of ultrasound impedance matching fluids on diffuse optical measurements
Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora
Author Affiliations +
Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 110742T (2019) https://doi.org/10.1117/12.2526925
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany
Abstract
Diffuse optical imaging can be used to probe highly scattering media like biological tissue down to a depth of few centimeters, with spatial resolution limited by light scattering. Its combination with ultrasound imaging can potentially lead to medical imaging systems with, for instance, high specificity in the examination of tumors. However, the presence of the ultrasound coupling gel between probe and tissue can have detrimental effects on the accuracy of optical imaging techniques. Here we present an experimental study on the effect of ultrasound coupling fluids on diffuse optical spectroscopy (DOS) and diffuse correlation spectroscopy (DCS). We demonstrate on tissue-mimicking phantoms that the use of standard water-clear gels, providing a direct path for the light from the source to the detection point, can distort optical measurements generating strong underestimation of both the absorption and the reduced scattering coefficients in DOS measurements, as well as underestimation of the Brownian diffusion coefficient in DCS measurements. On the contrary, various turbid fluids demonstrate excellent performance in preventing this issue.
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, and Alberto Dalla Mora "Effects of ultrasound impedance matching fluids on diffuse optical measurements", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110742T (11 July 2019); https://doi.org/10.1117/12.2526925
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 3 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Ultrasonography
Scattering
Optical testing
Tissues
Absorption
Fluid dynamics
Interfaces
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top