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Various samples of biodegradable polymers were studied with a phase-modulation laser interferometric microscope MIM-340 (Yekaterinburg, Russia) at a wavelength of 532 nm and magnification of x 20, with superficial plane resolution of up to 15 nm, vertical resolution of 0,1 nm and possibility to control the relief depth of up to 600 nm. We have performed an in vitro non-invasive assessment of the impact of the structure, composition and modification conditions of the obtained biopolymer composites on the viability, adhesive properties and functional activity of the living blood cells (neutrophils, lymphocytes, and platelets). We propose a number of densitometry criteria to identify the most promising biopolymer samples for the development of medical products with characteristics maximally resembling the physiological ones. |
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Biopolymers
Polymers
Composites
Laser interferometry
Mirrors
Blood
Interferometry
