Combined visible light optical coherence microscopy and fluorescence imaging setup to investigate 5-aminolevulinic acid postive glioma samples

Antonia Lichtenegger; Johanna Gesperger; Barbara Kiesel; Danielle J. Harper; Pablo Eugui; Matthias Salas; Marco Augustin; Thomas Roetzer; Christoph K. Hitzenberger; Georg Widhalm; Adelheid Woehrer; Bernhard Baumann

doi:10.1117/12.2526618

19 July 2019 Combined visible light optical coherence microscopy and fluorescence imaging setup to investigate 5-aminolevulinic acid postive glioma samples

Antonia Lichtenegger, Johanna Gesperger, Barbara Kiesel, Danielle J. Harper, Pablo Eugui, Matthias Salas, Marco Augustin, Thomas Roetzer, Christoph K. Hitzenberger, Georg Widhalm, Adelheid Woehrer, Bernhard Baumann

Author Affiliations +

Proceedings Volume 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III; 1107819 (2019) https://doi.org/10.1117/12.2526618
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

5-aminolevulinic acid positive brain tumor samples were investigated with a multimodal visible light optical coherence microscope (OCM) and fluorescence imaging (FI) setup. Tumor specific contrast was achieved by the FI part while the three-dimensional tissue morphology was assessed by the OCM part of the setup.

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Antonia Lichtenegger, Johanna Gesperger, Barbara Kiesel, Danielle J. Harper, Pablo Eugui, Matthias Salas, Marco Augustin, Thomas Roetzer, Christoph K. Hitzenberger, Georg Widhalm, Adelheid Woehrer, and Bernhard Baumann "Combined visible light optical coherence microscopy and fluorescence imaging setup to investigate 5-aminolevulinic acid postive glioma samples", Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III, 1107819 (19 July 2019); https://doi.org/10.1117/12.2526618

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KEYWORDS

Tumors

Brain

Luminescence

Tissues

Visible radiation

Neuroimaging

Mirrors

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