Ceruloplasmin: a potential carrier of photosensitizers for photodynamic therapy of tumors

Anna G. Gyulkhandanyan; Anna A. Zakoyana; Aram G. Gyulkhandanyan; Marina V. Parkhots; Boris M. Dzhagarov; Ekaterina N. Lazareva; Valery V. Tuchin; Grigor V. Gyulkhandanyana

doi:10.1117/12.2527568

22 July 2019 Ceruloplasmin: a potential carrier of photosensitizers for photodynamic therapy of tumors

Anna G. Gyulkhandanyan, Anna A. Zakoyana, Aram G. Gyulkhandanyan, Marina V. Parkhots, Boris M. Dzhagarov, Ekaterina N. Lazareva, Valery V. Tuchin, Grigor V. Gyulkhandanyana

Author Affiliations +

Proceedings Volume 11079, Medical Laser Applications and Laser-Tissue Interactions IX; 110791T (2019) https://doi.org/10.1117/12.2527568
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

The relevance and importance of the development of new areas of tumor therapy is defined in connection with a strong increase in the level of oncological diseases. The latest global cancer data indicates a high mortality rate: the incidence of cancer increases to 18.1 million new cases and 9.6 million cancer deaths in 2018. Advances in nanostructures and nanotechnologies at the molecular scale in future can revolutionize several aspects of the diagnosis and treatment of body tumors. Search of highly specific and highly effective new therapeutic compounds is one of the most important directions in treatment of oncological diseases by noninvasive way. Currently, in clinics method of photodynamic therapy (PDT) of tumors based on photosensitizers (PSs) and light irradiation is widely used. At its application, the cancer cells are unable to develop resistance to such method of destruction.

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Anna G. Gyulkhandanyan, Anna A. Zakoyana, Aram G. Gyulkhandanyan, Marina V. Parkhots, Boris M. Dzhagarov, Ekaterina N. Lazareva, Valery V. Tuchin, and Grigor V. Gyulkhandanyana "Ceruloplasmin: a potential carrier of photosensitizers for photodynamic therapy of tumors", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791T (22 July 2019); https://doi.org/10.1117/12.2527568

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