Single human platelet study using surface-enhanced Raman spectroscopy as a perspective tool for antiplatelet therapy effectiveness prediction

Andrey Y. Zyubin; Vladimir V. Rafalskiy; Anna V. Tcibulnikova; Karina I. Matveeva; Ekaterina M. Moiseeva; Viktoria V. Kolosova; Vladimir O. Misuk; Alina A. Tsapkova; Ilia G. Samusev

doi:10.1117/12.2536384

20 November 2019 Single human platelet study using surface-enhanced Raman spectroscopy as a perspective tool for antiplatelet therapy effectiveness prediction

Andrey Y. Zyubin, Vladimir V. Rafalskiy, Anna V. Tcibulnikova, Karina I. Matveeva, Ekaterina M. Moiseeva, Viktoria V. Kolosova, Vladimir O. Misuk, Alina A. Tsapkova, Ilia G. Samusev

Author Affiliations +

Proceedings Volume 11190, Optics in Health Care and Biomedical Optics IX; 111900K (2019) https://doi.org/10.1117/12.2536384
Event: SPIE/COS Photonics Asia, 2019, Hangzhou, China

Abstract

This paper describes detailed study of single human platelet and can be used for rapid and early structure changes and biomarkers identification in individuals with cardiovascular decease (CCD) pathology in vitro. The obtained data include analyzed Surface-enhanced Raman spectra (SERS) of human platelets taken from healthy individuals and individuals with cardiovascular pathology. Paper describes characteristic maxima of different cell components and its changes in platelets.

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Andrey Y. Zyubin, Vladimir V. Rafalskiy, Anna V. Tcibulnikova, Karina I. Matveeva, Ekaterina M. Moiseeva, Viktoria V. Kolosova, Vladimir O. Misuk, Alina A. Tsapkova, and Ilia G. Samusev "Single human platelet study using surface-enhanced Raman spectroscopy as a perspective tool for antiplatelet therapy effectiveness prediction", Proc. SPIE 11190, Optics in Health Care and Biomedical Optics IX, 111900K (20 November 2019); https://doi.org/10.1117/12.2536384

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