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20 November 2019 Toward artifact-free reconstruction of photoacoustic computed tomography images
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As an emerging optical imaging modality, photoacoustic imaging provides optical absorption contrasts and ultrasonic high resolution. Artifacts appearing in photoacoustic computed tomography (PACT) always deteriorate image quality and resolution, and result in confusion of biological information. On the basis of different causing reasons, they are roughly classified as split artifacts and streak artifacts. Here we present an innovative Feature-Coupling (FC) method to weaken split artifacts with joint reconstruction of speed of sound and a new reconstruction algorithm, termed Contamination-Tracing Back-Projection (CTBP), is proposed for the mitigation of streak artifacts. The utility, effectiveness and robustness of our methods were demonstrated using numerical, phantom, and in vivo experiments.
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Xuanhao Wang, Chuangjian Cai, Kexin Deng, and Cheng Ma "Toward artifact-free reconstruction of photoacoustic computed tomography images", Proc. SPIE 11190, Optics in Health Care and Biomedical Optics IX, 111901G (20 November 2019);

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