Chemical sensing based on silk coated exposed-core fibers

Lu Peng; Asma Khalid; Stephen C. Warren-Smith; Azim Arman; Erik P. Schartner; Georgina Maree Sylvia; Mark R. Hutchinson; Heike Ebendorff-Heidepriem; Robert A. McLaughlin; Brant C. Gibson; Jiawen Li

doi:10.1117/12.2541320

30 December 2019 Chemical sensing based on silk coated exposed-core fibers

Lu Peng, Asma Khalid, Stephen C. Warren-Smith, Azim Arman, Erik P. Schartner, Georgina Maree Sylvia, Mark R. Hutchinson, Heike Ebendorff-Heidepriem, Robert A. McLaughlin, Brant C. Gibson, Jiawen Li

Author Affiliations +

Proceedings Volume 11202, Biophotonics Australasia 2019; 112020G (2019) https://doi.org/10.1117/12.2541320
Event: ANZCOP, 2019, Melbourne, Australia

Abstract

We demonstrate in-vivo chemical sensing using silk-coated exposed-core microstructured optical fibers (ECFs). The ECF provides advantages in sensitivity due to the direct access of the fiber core to the surrounding environment with integrated measurement along the entire fiber length, rather than simply the fiber tip as is common in other probes. The silk coating provides an encapsulation of the sensor molecules, and is well known as a biocompatible material. This deployable fiber sensor is fabricated with simple splicing and coating techniques, making it practical to be used in a range of biomedical sensing applications, which we demonstrate through pH sensing in a mouse model.

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Lu Peng, Asma Khalid, Stephen C. Warren-Smith, Azim Arman, Erik P. Schartner, Georgina Maree Sylvia, Mark R. Hutchinson, Heike Ebendorff-Heidepriem, Robert A. McLaughlin, Brant C. Gibson, and Jiawen Li "Chemical sensing based on silk coated exposed-core fibers", Proc. SPIE 11202, Biophotonics Australasia 2019, 112020G (30 December 2019); https://doi.org/10.1117/12.2541320

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