Non-invasive, near infrared angiography by high-speed digital holography allows for blood flow imaging and measurement of quantitative hemodynamic parameters in the human eye with an unrivaled temporal resolution. It reveals blood flow contrasts in the retinal and choroidal vasculature and enables vessel type identification. We report the first results of a clinical trial involving laser Doppler holographic monitoring of the eye fundus (IMA-MODE), designed to assess the pathophysiology of a number of ocular and general diseases appearing with age, such as occlusions, hypertension and diabetes, which may affect the ocular circulation, and provoke potentially blinding microvascular damage.
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