Compact microLED optrode device for patterned inter-cortical optogenetics (Conference Presentation)

Niall McAlinden; Yunzhou Cheng; Robert Scharf; Enyuan Xie; Erdan Gu; Rohit Sharma; Prashant Tathireddy; Christopher F. Reiche; Martin D. Dawson; Loren Rieth; Steve Blair; Keith Mathieson

doi:10.1117/12.2550809

9 March 2020 Compact microLED optrode device for patterned inter-cortical optogenetics (Conference Presentation)

Niall McAlinden, Yunzhou Cheng, Robert Scharf, Enyuan Xie, Erdan Gu, Rohit Sharma, Prashant Tathireddy, Christopher F. Reiche, Martin D. Dawson, Loren Rieth, Steve Blair, Keith Mathieson

Author Affiliations +

Proceedings Volume 11226, Neural Imaging and Sensing 2020; 112261D (2020) https://doi.org/10.1117/12.2550809
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

There is current demand for pattern programmable devices that can deliver light to deep brain structures for use in optogenetic experiments. Here we introduce a microLED optrode device with 181 individually addressable sites, each with the capability to optogenetically excite thousands of neurons in vivo. The device consists of a 10 x 10 glass microneedle array directly integrated with a custom fabricated microLED device. 100 microLEDs couple to the needle tips for intra-cortical light delivery and 81 microLEDs sit at interstitial points for surface illumination. Light delivery and thermal properties are comprehensively evaluated.

Conference Presentation

Citation Download Citation

Niall McAlinden, Yunzhou Cheng, Robert Scharf, Enyuan Xie, Erdan Gu, Rohit Sharma, Prashant Tathireddy, Christopher F. Reiche, Martin D. Dawson, Loren Rieth, Steve Blair, and Keith Mathieson "Compact microLED optrode device for patterned inter-cortical optogenetics (Conference Presentation)", Proc. SPIE 11226, Neural Imaging and Sensing 2020, 112261D (9 March 2020); https://doi.org/10.1117/12.2550809

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