Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)

Seunghun Lee; Wonyeong Park; Seonghan Kim; Hoonchul Chang; Bumju Kim; Won Hyuk Jang; Younghoon Shin; Myoung Joon Kim; Euiheon Chung; Eui Hyun Kim; Kyung Hwa Lee; Ki Hean Kim

doi:10.1117/12.2546056

9 March 2020 Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)

Seunghun Lee, Wonyeong Park, Seonghan Kim, Hoonchul Chang, Bumju Kim, Won Hyuk Jang, Younghoon Shin, Myoung Joon Kim, Euiheon Chung, Eui Hyun Kim, Kyung Hwa Lee, Ki Hean Kim

Author Affiliations +

Proceedings Volume 11229, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII; 112291F (2020) https://doi.org/10.1117/12.2546056
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Surgical resection is the primary treatment for malignant brain tumors. This procedure has a dilemma—aggressive surgical resection tends to extend patient survival; however, it also increases the risk of neurological deficiencies. Current medical imaging methods are not sensitive and their interpretation largely depend on surgeon’s impression. High-speed cellular imaging method by using clinically applicable moxifloxacin was demonstrated for fast and sensitive tumor-detection. The detailed cytoarchitecture of brain tumor mouse model and malignant human brain tumors was revealed. This study showed the potential and feasibility of moxifloxacin-based confocal microscopy as a surgery-guiding method for tumor removal.

Conference Presentation

Citation Download Citation

Seunghun Lee, Wonyeong Park, Seonghan Kim, Hoonchul Chang, Bumju Kim, Won Hyuk Jang, Younghoon Shin, Myoung Joon Kim, Euiheon Chung, Eui Hyun Kim, Kyung Hwa Lee, and Ki Hean Kim "Fast and sensitive delineation of brain tumor with clinically compatible moxifloxacin labeling and confocal microscopy (Conference Presentation)", Proc. SPIE 11229, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIII, 112291F (9 March 2020); https://doi.org/10.1117/12.2546056

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available