PDMS-based Bragg diffraction grating glucose sensor integrable in a contact lens

Carla Dumitrascu; Maria Morant; Laura Mercadé; Todora Angelova; Roberto Llorente

doi:10.1117/12.2544876

20 February 2020 PDMS-based Bragg diffraction grating glucose sensor integrable in a contact lens

Carla Dumitrascu, Maria Morant, Laura Mercadé, Todora Angelova, Roberto Llorente

Proceedings Volume 11233, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX; 112330Q (2020) https://doi.org/10.1117/12.2544876
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

This paper proposes a glucose optical biosensor based on a Bragg diffraction grating fabricated in Poly(dimethylsiloxane) (or PDMS), suitable for integration in an ophthalmologic contact lens. One of the periodic layers of the grating is functionalized with Glucose Oxidase (GOx) to change its refractive index proportionally with glucose concentration and, therefore, modify the response of the resulting filter. Different layers are fabricated and characterized by spectroscopic ellipsometry considering different glucose concentrations. The proposed structure can detect changes in glucose levels from 80 mg/dl to 180 mg/dl, reducing its optical response to 65% at 521 nm, being capable of real-time, continuous and non-invasive sensing.

Conference Presentation

Citation Download Citation

Carla Dumitrascu, Maria Morant, Laura Mercadé, Todora Angelova, and Roberto Llorente "PDMS-based Bragg diffraction grating glucose sensor integrable in a contact lens", Proc. SPIE 11233, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XX, 112330Q (20 February 2020); https://doi.org/10.1117/12.2544876

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available