In vivo optical clearing of human light and dark skin (Conference Presentation)

Valery V. Tuchin; Elina A. Genina; Alexey N. Bashkatov; Ekaterina N. Lazareva; Vladimir P. Zharov

doi:10.1117/12.2566932

26 March 2020 In vivo optical clearing of human light and dark skin (Conference Presentation)

Valery V. Tuchin, Elina A. Genina, Alexey N. Bashkatov, Ekaterina N. Lazareva, Vladimir P. Zharov

Proceedings Volume 11239, Dynamics and Fluctuations in Biomedical Photonics XVII; 1123902 (2020) https://doi.org/10.1117/12.2566932
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

In this work, using 930-nm optical coherence tomography (OCT) and reflection spectroscopy in a wide wavelength range from UV to NIR, we investigated and confirmed the concept of the possibility of fast and efficient optical clearing of tissue, in particular human skin in vivo when using various agents and enhancers of skin permeability. The combination of a number of physico-chemical factors enhancing permeability increases the OCT signal several times with more than double the penetration depth. For dark skin and in the UV wavelength range, where absorption is high, optical clearing is not so effective, but everything is equally useful.

Conference Presentation

Citation Download Citation

Valery V. Tuchin, Elina A. Genina, Alexey N. Bashkatov, Ekaterina N. Lazareva, and Vladimir P. Zharov "In vivo optical clearing of human light and dark skin (Conference Presentation)", Proc. SPIE 11239, Dynamics and Fluctuations in Biomedical Photonics XVII, 1123902 (26 March 2020); https://doi.org/10.1117/12.2566932

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