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6 March 2020 Ultra-high-speed wide-field photoacoustic microscopy using a polygon mirror scanner (Conference Presentation)
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Abstract
Optical-resolution photoacoustic microscopy (OR-PAM) has become a popular tool in small-animal studies. However, previous OR-PAM techniques variously lacked a high imaging speed, a high spatial resolution, and/or a large field of view. Here we report a high-speed OR-PAM system using an innovative water-immersible polygon-mirror scanner, which has achieved a cross-sectional frame rate of as high as 1200 Hz over a 12-mm scanning range. Using this polygon-scanner-based OR-PAM system, we have performed various studies on mouse models with stroke and cardiac arrests. We expect that the new OR-PAM system will become a powerful tool for imaging hemodynamics and neuronal functions.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Junjie Yao, Bangxin Lan, Wei Liu, Qifa Zhou, Jun Zou, Ulrike Hoffmann, and Wei Yang "Ultra-high-speed wide-field photoacoustic microscopy using a polygon mirror scanner (Conference Presentation)", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112401W (6 March 2020); https://doi.org/10.1117/12.2543914
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