Elastic characterization of heterogeneous tissues using longitudinal shear waves in optical coherence elastography (Conference Presentation)

Fernando Zvietcovich; Gary R. Ge; Humberto Mestre; Michael Giannetto; Maiken Nedergaard; Jannick P. Rolland; Kevin J. Parker

doi:10.1117/12.2545388

9 March 2020 Elastic characterization of heterogeneous tissues using longitudinal shear waves in optical coherence elastography (Conference Presentation)

Fernando Zvietcovich, Gary R. Ge, Humberto Mestre, Michael Giannetto, Maiken Nedergaard, Jannick P. Rolland, Kevin J. Parker

Author Affiliations +

Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 112420X (2020) https://doi.org/10.1117/12.2545388
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Longitudinal shear waves (LSW) are waves with longitudinally polarized displacement that travel at the shear wave speed through depth when generated at the surface of tissues. In this study, we explore LSW generated by a circular glass plate in contact with the sample. Results demonstrated the potential of LSW in detecting an elasticity gradient along axial (resolution < 0.13 mm) and lateral (resolution < 0.78 mm) directions simultaneously. Finally, LSWs are used for the elastography of ex vivo mouse brain and demonstrated differentiated LSW speed values between the cerebral cortex (2.91 m/s) and cerebellum/midbrain (1.18 m/s) regions.

Conference Presentation

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Fernando Zvietcovich, Gary R. Ge, Humberto Mestre, Michael Giannetto, Maiken Nedergaard, Jannick P. Rolland, and Kevin J. Parker "Elastic characterization of heterogeneous tissues using longitudinal shear waves in optical coherence elastography (Conference Presentation)", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420X (9 March 2020); https://doi.org/10.1117/12.2545388

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