Why nonlinear Raman microspectroscopy is more than just a gimmick?

Anton Shutov; Georgi I. Petrov; Delong Zhang; Vladislav V. Yakovlev

doi:10.1117/12.2547179

11 March 2020 Why nonlinear Raman microspectroscopy is more than just a gimmick?

Anton Shutov, Georgi I. Petrov, Delong Zhang, Vladislav V. Yakovlev

Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 1125119 (2020) https://doi.org/10.1117/12.2547179
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Coherent Raman microspectroscopy utilizing either stimulated Raman scattering or coherent Raman scattering is gaining popularity in the field of biological imaging. It is generally assumed that coherent Raman spectroscopy provides a stronger signal than conventional spectroscopy based on spontaneous scattering, allowing much faster imaging. In this report we examine non-trivial advantages of coherent Raman microspectroscopy, which haven’t been given significant attention lately. In particular, we demonstrate the potential of improving sensitivity of Raman spectroscopy and ability to sense the local nanoenvironment.

Citation Download Citation

Anton Shutov, Georgi I. Petrov, Delong Zhang, and Vladislav V. Yakovlev "Why nonlinear Raman microspectroscopy is more than just a gimmick?", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125119 (11 March 2020); https://doi.org/10.1117/12.2547179

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