NIR-II fluorescence in vivo functional bioimaging

Jun Qian

doi:10.1117/12.2546992

21 February 2020 NIR-II fluorescence in vivo functional bioimaging

Jun Qian

Proceedings Volume 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII; 112540G (2020) https://doi.org/10.1117/12.2546992
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Fluorescence bioimaging in the second near-infrared spectral region (NIR-II, 900-1700 nm) can provide advantages of high spatial resolution and large penetration depth, due to low light scattering. In addition, since long-wavelength light with low photon energy is utilized as the excitation and less absorbed by the biological tissues, NIR-II fluorescence bioimaging also has low autofluorescence, as well as negligible photodamage towards biosamples. During the past few years, NIR-II fluorescence bioimaging has experienced rapid development. In this paper, we will introduce some recent research works about NIR-II fluorescence bioimaging in our research group, such as video-rate whole-body/brain/tumour angiography, organ imaging, as well as diagnosis and imaging guided treatment of tumour, on mice and monkeys.

Citation Download Citation

Jun Qian "NIR-II fluorescence in vivo functional bioimaging", Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112540G (21 February 2020); https://doi.org/10.1117/12.2546992

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