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10 March 2020 Super-resolution imaging using saturated absorption combined with spatial frequency modulated Imaging (Conference Presentation)
Patrick A. Stockton, Keith Wernsing, Jeff Field, Jeff Squier
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Proceedings Volume 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII; 112540P (2020) https://doi.org/10.1117/12.2546071
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
In recent years, we demonstrated a new approach to super-resolution microscopy based on driving a nonlinear interaction with a Spatial Frequency Modulated Imaging (SPIFI). SPIFI is a line imaging technique that linearly sweeps all the frequencies supported by the band-pass of the objective lens. Here we introduce a new method of unrestricted super-resolution imaging based on driving saturated absorption in the specimen excitation. The saturated absorption drives harmonic distortions of the spatial frequencies used to illuminate the sample. These harmonics manifest themselves as temporal harmonic frequencies allowing for easy detection and separation of the super-resolution information in the far field.
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Patrick A. Stockton, Keith Wernsing, Jeff Field, and Jeff Squier "Super-resolution imaging using saturated absorption combined with spatial frequency modulated Imaging (Conference Presentation)", Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112540P (10 March 2020); https://doi.org/10.1117/12.2546071
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KEYWORDS
Super resolution
Absorption
Spatial frequencies
Modulation
Coherence imaging
Diffraction
Optical microscopy
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