The bio-laser is an emerging technology in biosensing and imaging. In contrast to traditional fluorescence based measurement, lasing emission is used as the sensing signal, which has strong intensity, threshold behavior, and narrow linewidth, and is free of background. In this presentation, we will first discuss the principle of bio-lasers. Then we will describe the development of the laser emission microscope based on bio-lasers for tissue imaging that can be used for cancer diagnosis.
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