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16 March 2020 Preliminary imaging evaluation of a compact tomosynthesis system for potential point-of-care extremity imaging
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Orthopedic tomosynthesis is emerging as an attractive alternative to digital radiography (DR), with increased sensitivity for some clinical tasks, including fracture diagnosis and staging and follow-up of arthritis. Commercially available digital tomosynthesis (DTS) systems are complex, room-sized devices. A compact tomosynthesis system for extremity imaging (TomoE) was previously demonstrated using carbon nanotube (CNT) x-ray source array technology. The purpose of this study was to evaluate the prototype device in preparation for an Institutional Review Board (IRB)- approved patient imaging study and evaluate initial patient images.

A tabletop device was constructed using a short CNT x-ray source array, operated in three positions, and a flat panel digital detector. Twenty-one x-ray projection images were acquired at incident angles from -20 to +20 degrees in various clinical orientations, with entrance doses matched to commercial in-room DTS scanners. The projection images were reconstructed with an iterative reconstruction technique in 1mm slices. Cadaveric specimen and initial participant images were reviewed by radiologists for feature conspicuity and diagnostic accuracy.

TomoE image quality was found to be superior to DR, with reconstruction slices exhibiting visual conspicuity of trabecular bone, delineation of joint space, bone erosions, fractures, and clear depiction of normal anatomical features. The scan time was fifteen seconds with mechanical translation. Skin entrance dose was verified to be 0.2mGy. TomoE device image quality has been evaluated in cadaveric specimens and dose was calibrated for a patient imaging study. Initial patient images depict a high level of anatomical detail an increase in diagnostic value compared to DR.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christina R. Inscoe, Alex J. Billingsley, Connor Puett, Daniel Nissman, Jianping Lu, Yueh Z. Lee, and Otto Z. Zhou "Preliminary imaging evaluation of a compact tomosynthesis system for potential point-of-care extremity imaging", Proc. SPIE 11312, Medical Imaging 2020: Physics of Medical Imaging, 1131204 (16 March 2020);

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