Submillimeter-wave imaging assisted alignment of millimeter-wave spectroscopic system for quantification of corneal water content

Mariangela Baggio; Yong Hu; Aleksi Tamminen; Irina Nefedova; Juha Ala-Laurinaho; Zachary Taylor

doi:10.1117/12.2556309

6 April 2020 Submillimeter-wave imaging assisted alignment of millimeter-wave spectroscopic system for quantification of corneal water content

Mariangela Baggio, Yong Hu, Aleksi Tamminen, Irina Nefedova, Juha Ala-Laurinaho, Zachary Taylor

Author Affiliations +

Proceedings Volume 11348, Terahertz Photonics; 113480M (2020) https://doi.org/10.1117/12.2556309
Event: SPIE Photonics Europe, 2020, Online Only

Abstract

We propose an alignment strategy for millimeter spectroscopy of cornea that uses imaging to screen for sufficient alignment conditions. The performance of different corneal imaging objectives, in the presence of misalignment, is evaluated. The cornea is illuminated with a TEM00 Gaussian beam at 650 GHz and the beam is swept across the cornea. Images are generated by calculating the coupling between illumination and scattered beams for each illumination beam position and angle. The cornea is displaced at intervals of 500 microns in the transverse and axial directions and with new coupling coefficient maps generated at each misaligned position. Contrast in the misaligned cases are compared to the aligned case via zero normalized spatial cross correlation. The results show a maximum normalized cross correlation of 0.92 for a two-mirror scanning system and 0.74 for a one-mirror scanning objective. The analysis suggests that imaging contrast at 650 GHz can be used to screen for misalignment that would be difficult to detect with MMW.

Citation Download Citation

Mariangela Baggio, Yong Hu, Aleksi Tamminen, Irina Nefedova, Juha Ala-Laurinaho, and Zachary Taylor "Submillimeter-wave imaging assisted alignment of millimeter-wave spectroscopic system for quantification of corneal water content", Proc. SPIE 11348, Terahertz Photonics, 113480M (6 April 2020); https://doi.org/10.1117/12.2556309

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